| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pestis |
| 靶标 | Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla |
| 免疫原 | E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P17811 |
| 背景信息 | Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity. 1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417 2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135 3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282 4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 羊抗鸡IgY抗体(精品) | 8437 |
| 鼠抗人IgG(单抗) | 7868 |
| 鼠抗人IgM(单抗) | 8322 |
| 新冠病毒N单抗IgG人源化质控品 | 8590 |
| 新冠病毒N单抗IgM人源化质控品 | 8294 |
| 三聚氰胺单抗 | 7988 |
| 纳他霉素单抗 | 8512 |
| 孔雀石绿单抗 | 8242 |
| 隐性孔雀石绿单抗 | 8300 |
| 微囊藻毒素LR单抗 | 8012 |
| 黄曲霉毒素B1单抗 | 8012 |
| 黄曲霉毒素M1单抗 | 7289 |
| T2毒素单抗 | 7891 |
| 赭曲霉毒素单抗 | 7602 |
| 呕吐毒素单抗 | 7730 |
| 伏马毒素单抗 | 8104 |
| 黄曲霉总量单抗B1 | 7291 |
| 黄曲霉总量单抗B2 | 7893 |
| 黄曲霉总量单抗G1 | 7417 |
| 黄曲霉总量单抗G2 | 7315 |