| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pestis |
| 靶标 | Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla |
| 免疫原 | E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P17811 |
| 背景信息 | Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity. 1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417 2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135 3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282 4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
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| 甲砜霉素20H10单抗 | 7388 |
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| 链霉素20H5单抗 | 7533 |
| 磺胺类SAS抗体 | 8139 |
| 有机磷单抗 | 8138 |
| 莱克多巴胺单抗 | 8730 |
| 克伦特罗单抗 | 9116 |
| 甲状腺素(T4)单抗 | 8953 |
| 三碘甲状腺原氨酸(T3)单抗 | 8799 |
| 新冠病毒N蛋白配对抗体 | 8753 |
| 叶酸单抗 | 8937 |
| 抗猪乙型脑炎单克隆抗体 | 5654 |
| 抗猪圆环病毒 2 型单克隆抗体 | 6564 |
| 抗猪蓝耳病毒单克隆抗体 | 6279 |
| 抗猪圆环病毒 3 型/4型单克隆抗体 | 6485 |
| 抗猪细小病毒单克隆抗体 | 6497 |
| 抗口蹄疫 O 型、亚洲一型单克隆抗体 | 6579 |
| 抗经典猪瘟单克隆抗体 | 5895 |
| 抗猪流行性腹泻单克隆抗体 | 5715 |