| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pestis |
| 靶标 | Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla |
| 免疫原 | E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P17811 |
| 背景信息 | Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity. 1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417 2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135 3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282 4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 心型脂肪酸结合蛋白鼠单抗 | 8355 |
| D-二聚体 G1 鼠单抗 | 8559 |
| D-二聚体 G2 鼠单抗 | 8710 |
| D-二聚体 G 鼠单抗 | 8370 |
| 抗人降钙素原鼠单抗 | 8541 |
| 抗人CRP鼠单抗 | 8552 |
| 抗人CRP鼠单抗-HRP | 8129 |
| 抗人SAA IgG鼠单抗 | 8469 |
| 抗生物素单抗 | 8319 |
| α-hcg单抗 | 7948 |
| β-hcg单抗 | 8301 |
| HIV配对鼠单抗 | 8381 |
| 脂蛋白小a鼠单抗 | 8211 |
| 红斑狼疮补体鼠单抗 | 8234 |
| 维生素D VDS鼠单抗 | 8207 |
| 二十五羟基维生素D3鼠单抗 | 8547 |
| 羊抗鼠抗体(定性) | 8214 |
| 羊抗鼠抗体(定量) | 8286 |
| RBC鼠单抗 | 8239 |
| HRP羊抗人抗体(精品) | 8432 |