| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Yersinia pestis |
| 靶标 | Coagulase/fibrinolysin, EC:3.4.23.48, Pla, Plasminogen activator, pla |
| 免疫原 | E. coli - derived recombinant Yersinia pestis Plasminogen activator/Pla (Ala21-Phe312). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P17811 |
| 背景信息 | Plasminogen activator is a ~34 kDa protein. In the mammalian host activates (cleaves) plasminogen to generate the serine protease plasmin. Plasmin degrades fibrin clots (fibrinolysis) and facilitates bacterial cell migration, enabling rapid dissemination of bacteria from the initial site of infection (Probable). Cleaves host plasminogen to generate plasmin and probably also has autocatalytic activity. Fibrinolytic activity prevails at 37 degrees Celsius whereas coagulase expression predominates at lower temperatures (28 degrees Celsius). Cleaves plasminogen; plasminogen cleavage is much higher than coagulase activity. 1. Eren, E. et al. (2010) Structure (London, England : 1993) 18, 809-18. PMID: 20637417 2. Eren, E. et al. (2012) The Journal of biological chemistry 287, 23971-6. PMID: 22645135 3. McDonough, KA. et al. (1989) Molecular microbiology 3, 767-75. PMID: 2526282 4. Sodeinde, OA. et al. (1989) Infection and immunity 57, 1517-23. PMID: 2651310 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| Trx鼠单抗标签 | 8127 |
| BrdU单抗 | 8130 |
| HRP-BrdU单抗 | 7836 |
| GAPDH 鼠单抗 | 7753 |
| HRP-GAPDH 鼠单抗 | 7740 |
| PCNA单抗 | 8278 |
| α-tubulin 鼠单抗 | 7703 |
| β-tubulin 鼠单抗 | 8228 |
| HRP-β-tubulin 鼠单抗 | 8006 |
| β-Actin 鼠单抗 | 8088 |
| HRP-β-Actin 鼠单抗 | 7677 |
| Histone H3鼠单抗 | 7853 |
| 糖基化血红蛋白单抗 | 8161 |
| 糖基化血红蛋白抗体 | 8021 |
| C肽鼠单抗 | 7306 |
| 胰岛素鼠单抗 | 7914 |
| 胃蛋白酶原II鼠单抗 | 8032 |
| 鼠抗人胃泌素17单抗 | 7781 |
| 心肌钙蛋白鼠单抗(CTNI抗体) | 7884 |
| 肌红蛋白鼠单抗 | 8048 |