| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin |
| 免疫原 | E. coli - derived recombinant Human NOCT (Thr120-Ser431). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UK39 |
| 背景信息 | Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. 1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539 2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 羊抗鸡IgY抗体(精品) | 7488 |
| 鼠抗人IgG(单抗) | 7014 |
| 鼠抗人IgM(单抗) | 7283 |
| 新冠病毒N单抗IgG人源化质控品 | 7772 |
| 新冠病毒N单抗IgM人源化质控品 | 7420 |
| 三聚氰胺单抗 | 7025 |
| 纳他霉素单抗 | 7414 |
| 孔雀石绿单抗 | 7097 |
| 隐性孔雀石绿单抗 | 7217 |
| 微囊藻毒素LR单抗 | 7118 |
| 黄曲霉毒素B1单抗 | 6841 |
| 黄曲霉毒素M1单抗 | 6430 |
| T2毒素单抗 | 6861 |
| 赭曲霉毒素单抗 | 6688 |
| 呕吐毒素单抗 | 6774 |
| 伏马毒素单抗 | 7080 |
| 黄曲霉总量单抗B1 | 6264 |
| 黄曲霉总量单抗B2 | 6780 |
| 黄曲霉总量单抗G1 | 6547 |
| 黄曲霉总量单抗G2 | 6424 |