| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin |
| 免疫原 | E. coli - derived recombinant Human NOCT (Thr120-Ser431). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UK39 |
| 背景信息 | Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. 1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539 2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 心型脂肪酸结合蛋白鼠单抗 | 7427 |
| D-二聚体 G1 鼠单抗 | 7436 |
| D-二聚体 G2 鼠单抗 | 7657 |
| D-二聚体 G 鼠单抗 | 7314 |
| 抗人降钙素原鼠单抗 | 7471 |
| 抗人CRP鼠单抗 | 7308 |
| 抗人CRP鼠单抗-HRP | 7050 |
| 抗人SAA IgG鼠单抗 | 7556 |
| 抗生物素单抗 | 7331 |
| α-hcg单抗 | 7054 |
| β-hcg单抗 | 7161 |
| HIV配对鼠单抗 | 7345 |
| 脂蛋白小a鼠单抗 | 7294 |
| 红斑狼疮补体鼠单抗 | 7171 |
| 维生素D VDS鼠单抗 | 7321 |
| 二十五羟基维生素D3鼠单抗 | 7456 |
| 羊抗鼠抗体(定性) | 7121 |
| 羊抗鼠抗体(定量) | 7464 |
| RBC鼠单抗 | 7401 |
| HRP羊抗人抗体(精品) | 7311 |