| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72 |
| 免疫原 | E. coli - derived recombinant Human DDX17 (Glu137-Gly556). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q92841 |
| 背景信息 | Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. 1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182 2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867 3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728 4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5716 |
| 西马特罗单抗 | 5695 |
| 孕酮单抗 | 5889 |
| 氯霉素(CAP)单抗 | 5825 |
| 红霉素单抗 | 5792 |
| 地克珠利单抗 | 5604 |
| 无色孔雀石绿(LMG)单抗 | 5826 |
| 雌二醇单抗 | 5445 |
| 孔雀石绿(MG)单抗 | 5982 |
| 双酚A单抗 | 5757 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5626 |
| 己烯雌酚单抗 | 5631 |
| 莱克多巴胺(RAC)单抗 | 5795 |
| 林可霉素单抗 | 5986 |
| 抗青霉素受体单抗 | 5628 |
| 大观霉素单抗 | 5687 |
| 克伦特罗(CL)单抗 | 5903 |
| 沙拉沙星单抗(2H4) | 5715 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5885 |
| 磺胺类SAS单抗 | 5826 |