| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72 |
| 免疫原 | E. coli - derived recombinant Human DDX17 (Glu137-Gly556). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q92841 |
| 背景信息 | Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. 1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182 2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867 3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728 4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5543 |
| 金刚烷胺单抗 | 5601 |
| 卡那霉素单抗 | 5750 |
| 黄曲霉毒素M1(AFM1)单抗 | 5706 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5918 |
| 帕托珠利(妥曲珠利砜)单抗 | 5613 |
| 泰乐菌素单抗 | 5665 |
| 替米考星单抗 | 5789 |
| 新霉素单抗 | 5758 |
| 安普霉素单抗 | 5713 |
| 三聚氰胺(MEL)单抗 | 5612 |
| 双氟沙星单抗 | 5567 |
| 西地那非单抗 | 5680 |
| 阿苯达唑单抗 | 5467 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5650 |
| 氟苯尼考单抗 | 5680 |
| 诺龙单抗 | 5750 |
| 达氟沙星单抗 | 5879 |
| 培氟沙星单抗 | 5727 |
| 庆大霉素单抗 | 5875 |