| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | 3'-5' RNA exonuclease OLD35, EC:2.7.7.8, PNPASE, PNPT1, PNPase 1, PNPase old-35, Polynucleotide phosphorylase 1, Polynucleotide phosphorylase-like protein, Polyribonucleotide nucleotidyltransferase 1, |
| 免疫原 | E. coli - derived recombinant Human PNPT1 (Gly43-Lys595). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8TCS8 |
| 背景信息 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) is a ~85 kDa protein. RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. 1. Pietras, Z. et al. (2018) Nature communications 9, 2558. PMID: 29967381 2. Kim, S. et al. (2024) Molecular cell 84, 2935-2948.e7. PMID: 39019044 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5700 |
| 西马特罗单抗 | 5675 |
| 孕酮单抗 | 5876 |
| 氯霉素(CAP)单抗 | 5803 |
| 红霉素单抗 | 5771 |
| 地克珠利单抗 | 5580 |
| 无色孔雀石绿(LMG)单抗 | 5807 |
| 雌二醇单抗 | 5433 |
| 孔雀石绿(MG)单抗 | 5971 |
| 双酚A单抗 | 5737 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5612 |
| 己烯雌酚单抗 | 5608 |
| 莱克多巴胺(RAC)单抗 | 5776 |
| 林可霉素单抗 | 5946 |
| 抗青霉素受体单抗 | 5611 |
| 大观霉素单抗 | 5669 |
| 克伦特罗(CL)单抗 | 5886 |
| 沙拉沙星单抗(2H4) | 5698 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5871 |
| 磺胺类SAS单抗 | 5806 |