| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | 3'-5' RNA exonuclease OLD35, EC:2.7.7.8, PNPASE, PNPT1, PNPase 1, PNPase old-35, Polynucleotide phosphorylase 1, Polynucleotide phosphorylase-like protein, Polyribonucleotide nucleotidyltransferase 1, |
| 免疫原 | E. coli - derived recombinant Human PNPT1 (Gly43-Lys595). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8TCS8 |
| 背景信息 | Polyribonucleotide nucleotidyltransferase 1, mitochondrial (PNPT1) is a ~85 kDa protein. RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules. 1. Pietras, Z. et al. (2018) Nature communications 9, 2558. PMID: 29967381 2. Kim, S. et al. (2024) Molecular cell 84, 2935-2948.e7. PMID: 39019044 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5515 |
| 金刚烷胺单抗 | 5571 |
| 卡那霉素单抗 | 5723 |
| 黄曲霉毒素M1(AFM1)单抗 | 5689 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5870 |
| 帕托珠利(妥曲珠利砜)单抗 | 5595 |
| 泰乐菌素单抗 | 5642 |
| 替米考星单抗 | 5753 |
| 新霉素单抗 | 5747 |
| 安普霉素单抗 | 5683 |
| 三聚氰胺(MEL)单抗 | 5595 |
| 双氟沙星单抗 | 5546 |
| 西地那非单抗 | 5664 |
| 阿苯达唑单抗 | 5451 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5622 |
| 氟苯尼考单抗 | 5657 |
| 诺龙单抗 | 5727 |
| 达氟沙星单抗 | 5845 |
| 培氟沙星单抗 | 5707 |
| 庆大霉素单抗 | 5853 |