| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | G17, N-system amino acid transporter 1, NAT1, Na(+)-coupled neutral amino acid transporter 3, SLC38A3, SN1, SNAT3, Sodium-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, S |
| 免疫原 | E. coli - derived recombinant Human SLC38A3 (Lys234-Asn323). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q99624 |
| 背景信息 | Sodium-coupled neutral amino acid transporter 3 (SLC38A3) is a ~55 kDa protein. Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from astrocytes in the intercellular space for the replenishment of both neurotransmitters glutamate and gamma-aminobutyric acid (GABA) in neurons and also functions as the major influx transporter in ganglion cells mediating the uptake of glutamine. The transport activity is specific for L-glutamine, L-histidine and L-asparagine. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). The transport is pH dependent, saturable, Li(+) tolerant and functions in both direction depending on the concentration gradients of its substrates and cotransported ions. 1. Fei, YJ. et al. (2000) The Journal of biological chemistry 275, 23707-17. PMID: 10823827 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5681 |
| 西马特罗单抗 | 5648 |
| 孕酮单抗 | 5856 |
| 氯霉素(CAP)单抗 | 5786 |
| 红霉素单抗 | 5754 |
| 地克珠利单抗 | 5563 |
| 无色孔雀石绿(LMG)单抗 | 5786 |
| 雌二醇单抗 | 5417 |
| 孔雀石绿(MG)单抗 | 5954 |
| 双酚A单抗 | 5712 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5598 |
| 己烯雌酚单抗 | 5586 |
| 莱克多巴胺(RAC)单抗 | 5755 |
| 林可霉素单抗 | 5904 |
| 抗青霉素受体单抗 | 5605 |
| 大观霉素单抗 | 5646 |
| 克伦特罗(CL)单抗 | 5861 |
| 沙拉沙星单抗(2H4) | 5684 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5854 |
| 磺胺类SAS单抗 | 5781 |