| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | G17, N-system amino acid transporter 1, NAT1, Na(+)-coupled neutral amino acid transporter 3, SLC38A3, SN1, SNAT3, Sodium-coupled neutral amino acid transporter 3, Solute carrier family 38 member 3, S |
| 免疫原 | E. coli - derived recombinant Human SLC38A3 (Lys234-Asn323). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q99624 |
| 背景信息 | Sodium-coupled neutral amino acid transporter 3 (SLC38A3) is a ~55 kDa protein. Symporter that cotransports specific neutral amino acids and sodium ions, coupled to an H(+) antiporter activity. Mainly participates in the glutamate-GABA-glutamine cycle in brain where it transports L-glutamine from astrocytes in the intercellular space for the replenishment of both neurotransmitters glutamate and gamma-aminobutyric acid (GABA) in neurons and also functions as the major influx transporter in ganglion cells mediating the uptake of glutamine. The transport activity is specific for L-glutamine, L-histidine and L-asparagine. The transport is electroneutral coupled to the cotransport of 1 Na(+) and the antiport of 1 H(+). The transport is pH dependent, saturable, Li(+) tolerant and functions in both direction depending on the concentration gradients of its substrates and cotransported ions. 1. Fei, YJ. et al. (2000) The Journal of biological chemistry 275, 23707-17. PMID: 10823827 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5499 |
| 金刚烷胺单抗 | 5535 |
| 卡那霉素单抗 | 5703 |
| 黄曲霉毒素M1(AFM1)单抗 | 5676 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5830 |
| 帕托珠利(妥曲珠利砜)单抗 | 5585 |
| 泰乐菌素单抗 | 5624 |
| 替米考星单抗 | 5723 |
| 新霉素单抗 | 5726 |
| 安普霉素单抗 | 5659 |
| 三聚氰胺(MEL)单抗 | 5579 |
| 双氟沙星单抗 | 5501 |
| 西地那非单抗 | 5645 |
| 阿苯达唑单抗 | 5440 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5605 |
| 氟苯尼考单抗 | 5636 |
| 诺龙单抗 | 5713 |
| 达氟沙星单抗 | 5827 |
| 培氟沙星单抗 | 5689 |
| 庆大霉素单抗 | 5839 |