Anti-Human OPRK1 Polyclonal Antibody|抗人OPRK1多克隆抗体(靶标：人κ型阿片受体)
- 货号：RB9THW387014
- 价格：面议
- 点击：572
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Homo sapiens (Human) |
| 靶标 | K-OR-1, KOR-1, Kappa-type opioid receptor, OPRK, OPRK1 |
| 免疫原 | E. coli - derived recombinant Human OPRK1 (Asp2-Ala57&Asp334-Val380). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P41145 |
| 背景信息 | Kappa-type opioid receptor (OPRK1) is a ~42 kDa protein. G-protein coupled opioid receptor that functions as a receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as a receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. |
| 备注 | For research use only |
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