Recombinant Human IL-10
- 货号：EPT295
- 价格：￥1,800.00 元
- 点击：605
产品介绍
基本信息
| 规格 | 10ug |
|---|---|
| 表达宿主 | Human Cells |
| 标签 | NA |
物理性质
| 分子量 | 18.6 KDa |
|---|---|
| 表观分子量 | 16 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein and belongs to the IL-10 family. IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts . IL-10 is an anti-inflammatory TH2 cytokine that has a critical role in limiting the immune response to pathogens to prevent host damage. As IL-10 in produced in several T helper populations, it is proposed that it provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed, IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. As IL-10 is a strong inhibitor of inflammation, it has become a viable biomarker for various diseases and conditions as well as a therapeutic molecule for certain conditions. In addition to elevated levels in parasitic infection, high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 虫螨腈（溴虫腈）-BSA（或OVA）抗原 | 4058 |
| 吡唑醚菌酯-BSA（或OVA）抗原 | 4222 |
| 烯酰吗啉-BSA（或OVA）抗原 | 4096 |
| 抑霉唑-BSA（或OVA）抗原 | 4267 |
| 恶醚唑（苯醚甲环唑）-BSA（或OVA）抗原 | 4253 |
| 辛硫磷-BSA（或OVA）抗原 | 4200 |
| 赛拉嗪（甲苯噻嗪）-BSA（或OVA）抗原 | 4309 |
| 倍硫磷-BSA（或OVA）抗原 | 4181 |
| 对硫磷-BSA（或OVA）抗原 | 4090 |
| 丙溴磷-BSA（或OVA）抗原 | 4177 |
| 戊唑醇-BSA（或OVA）抗原 | 4230 |
| 莠去津-BSA（或OVA）抗原 | 4236 |
| 灭蝇胺-BSA（或OVA）抗原 | 4043 |
| 2,4-二氯苯氧乙酸-BSA（或OVA）抗原 | 3963 |
| 左旋咪唑-BSA（或OVA）抗原 | 4038 |
| 三唑磷-BSA（或OVA）抗原 | 4170 |
| 氢氯噻嗪-BSA（或OVA）抗原 | 4132 |
| 甲基异柳磷-BSA（或OVA）抗原 | 4111 |
| 乙草胺-BSA（或OVA）抗原 | 4055 |
| 玉米赤霉烯酮-BSA（或OVA）抗原 | 4173 |