Recombinant Human IL-10
- 货号：EPT295
- 价格：￥1,800.00 元
- 点击：609
产品介绍
基本信息
| 规格 | 10ug |
|---|---|
| 表达宿主 | Human Cells |
| 标签 | NA |
物理性质
| 分子量 | 18.6 KDa |
|---|---|
| 表观分子量 | 16 KDa, reducing conditions |
| 形态 | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| 纯度 | Greater than 95% as determined by reducing SDS-PAGE. |
活性与内毒素
| 内毒素水平 | Less than 0.001 ng/µg (0.01 EU/µg) as determined by LAL test. |
|---|
储存与运输
| 溶解方法 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
|---|---|
| 储存方法 | Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
详细说明
| 背景说明 | Interleukin 10(IL10), also known as cytokine synthesis inhibitory factor (CSIF),is a secreted protein and belongs to the IL-10 family. IL-10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts . IL-10 is an anti-inflammatory TH2 cytokine that has a critical role in limiting the immune response to pathogens to prevent host damage. As IL-10 in produced in several T helper populations, it is proposed that it provides a feedback loop to limit the effector functions of macrophages and DCs on T cells. Once expressed, IL-10 signals through the IL-10 receptor (IL-10R) to activate STAT3. As IL-10 is a strong inhibitor of inflammation, it has become a viable biomarker for various diseases and conditions as well as a therapeutic molecule for certain conditions. In addition to elevated levels in parasitic infection, high expression levels of IL-10 are also found in retroviral infections inducing immunodeficiency. The immunosuppressive properties of IL-10 suggest a possible clinical use of IL-10 in suppressing rejections of grafts after organ transplantations |
|---|
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 杀螟硫磷-BSA（或OVA）抗原 | 3869 |
| 二嗪磷-BSA（或OVA）抗原 | 3923 |
| 甲基对硫磷-BSA（或OVA）抗原 | 4000 |
| 氯苯那敏-BSA（或OVA）抗原 | 4032 |
| 水胺硫磷-BSA（或OVA抗原） | 3862 |
| 泰拉霉素-BSA（或OVA）抗原 | 3967 |
| 二甲戊灵-BSA（或OVA）抗原 | 4080 |
| 腐霉利-BSA（或OVA）抗原 | 3895 |
| 甲基睾酮-BSA（或OVA）抗原 | 3966 |
| 醋酸美伦孕酮-BSA（或OVA）抗原 | 3956 |
| 硝呋烯腙-BSA（或OVA）抗原 | 3941 |
| 倍他米松-BSA（或OVA）抗原 | 4072 |
| 福莫特罗-BSA（或OVA）抗原 | 3765 |
| 替硝唑-BSA（或OVA）抗原 | 3919 |
| 布洛芬-BSA（或OVA）抗原 | 3941 |
| 地昔尼尔-BSA（或OVA）抗原 | 3914 |
| 2,4,5-三氯苯氧乙酸-BSA（或OVA）抗原 | 4041 |
| 4-氯苯氧乙酸-BSA（或OVA）抗原 | 3847 |
| 赤霉素-BSA（或OVA）抗原 | 4021 |
| 6-苄氨基嘌呤-BSA（或OVA）抗原 | 3823 |