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抗NPM1/ALK抗体(Anti-NPM1/ALK antibody - BSA and Azide free)

  • 货号:RB9A37029990
  • 价格:面议
  • 点击:1744
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产品介绍

产品描述

中文名称重组Anti-NPM1/ALK抗体 - BSA and Azide free
英文名称Anti-NPM1/ALK antibody - BSA and Azide free
别名CD246、ALK tyrosine kinase receptor、Anaplastic lymphoma kinase、ALK
靶点符号ALK
产品类型一抗

关键信息

宿主种属Rabbit
克隆Monoclonal
亚型IgG
不含载体蛋白Yes
反应种属Human
应用IHC-P
免疫原The exact immunogen used to generate this antibody is proprietary information.
特异性In more than 50% of systemic Anaplastic large cell lymphoma, t(2;5)(p23;q35) translocation can be found (Falini et al., 1999; Morris et al., 2001). (PMID: 9736036 and PMID: 11380391). The corresponding genes have been cloned and represent a fusion between the NPM and the ALK genes (Morris et al., 1994). (PMID: 8122112). Encodes a chimeric 80-kDa protein consisting of the N-terminal portion (amino acids 1-117) of NPM fused to the cytoplasmic portion of ALK (amino acids 1058-1620). Reference: Galietta et al., 2007. (PMID: 17537995).

反应性数据

应用应用代码物种验证状态备注
Immunocytochemistry/ ImmunofluorescenceICCIFHuman不推荐
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)IHCPHuman已验证The immunostaining was performed on a Leica Biosystems BOND ® RX instrument. Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

储存与纯化

形式Liquid
纯化工艺Affinity purification Protein A
存储溶液pH: 7.2 - 7.4 Constituents: PBS
储存信息Do Not Freeze
【仅供科学研究使用】

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