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抗DNA:RNA杂交体抗体（Anti-DNA:RNA hybrid antibody）
- 货号：RB9A37022192
- 价格：面议
- 点击：1167
产品介绍
产品描述
| 中文名称 | 重组Anti-DNA:RNA hybrid抗体 |
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| 英文名称 | Anti-DNA:RNA hybrid antibody |
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| 靶点符号 | DNA |
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| 产品类型 | 一抗 |
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关键信息
| 宿主种属 | Mouse |
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| 克隆 | Monoclonal |
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| 亚型 | IgG2a |
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| 轻链类型 | kappa |
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| 不含载体蛋白 | No |
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| 应用 | IP、Dot |
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| 免疫原 | The exact immunogen used to generate this antibody is proprietary information. |
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| 特异性 | The S9.6 monoclonal recognizes DNA-RNA hybrids (also known as R-loops) and does not bind to single or double stranded DNA (PubMed IDs: 2422282, 16614443). The antibody has high affinity for DNA-RNA hybrids but also binds RNA-RNA hybrids that are AU-rich (PubMed ID: 23784994). The specificity of the antibody appears to be determined by a combination of sequence and structural dependency since R-loop sequence affects binding affinity (PubMed ID: 28594954). It is important to use controls such as RNase A treatment in light of the cross-reactivity with double stranded RNA. Please see our DNA-RNA-IP (DRIP) protocol for further information. We do not recommend using this antibody for imaging applications such as ICC-IF, IHC or Flow due to the cross-reactivity with double stranded RNA. |
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储存与纯化
| 形式 | Liquid |
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| 纯化工艺 | Affinity purification Protein A |
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| 存储溶液 | pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA |
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| 推荐的短期储存时间 | 1-2 weeks |
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| 储存信息 | Avoid freeze / thaw cycle |
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