当前位置:首页>产品中心>单抗/多抗>Anti-Mouse MAdCAM-1 Recombinant Antibody|抗小鼠MAdCAM-1重组抗体(靶标:小鼠黏膜地址素细胞黏附分子1)

Anti-Mouse MAdCAM-1 Recombinant Antibody|抗小鼠MAdCAM-1重组抗体(靶标:小鼠黏膜地址素细胞黏附分子1)

  • 货号:RB9TMC589023
  • 价格:面议
  • 点击:844
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产品介绍

产品参数

形态Liquid
宿主种属Rat
克隆性Monoclonal
抗体亚型IgG2a, kappa
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
内毒素水平Please contact with the lab for this information.
应用IP, WP, Block, FCM, IHC
种属反应性Mus musculus (Mouse)
靶标MAdCAM-1, Madcam1, Mucosal addressin cell adhesion molecule 1, mMAdCAM-1
储存缓冲液0.01M PBS pH 7.4
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重构方法Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
登录号Q61826
背景信息

Mucosal addressin cell adhesion molecule 1 (MAdCAM-1) is a ~43 kDa protein. Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can bind both the integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of leukocytes. Both isoform 1 and isoform 2 can adhere to integrin alpha-4/beta-7. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding.

备注For research use only
【仅供科学研究使用】

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