Anti-Mouse F2RL1 Polyclonal Antibody|抗小鼠F2RL1多克隆抗体(靶标：小鼠凝血因子Ⅱ受体样1/PAR2)
- 货号：RB9TMX041014
- 价格：面议
- 点击：660
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mus musculus (Mouse) |
| 靶标 | Proteinase-activated receptor 2; PAR-2; Coagulation factor II receptor-like 1; G-protein coupled receptor 11; Thrombin receptor-like 1; F2rl1; Gpcr11; Gpr11; Par2 |
| 免疫原 | E. coli - derived recombinant Mouse F2RL1 (Ser39-Gly73&Met214-Leu237&Ser350-Tyr399). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P55086 |
| 背景信息 | Proteinase-activated receptor 2 (F2RL1) is a ~44 kDa protein. Receptor for trypsin and trypsin-like enzymes coupled to G proteins. Its function is mediated through the activation of several signaling pathways including phospholipase C (PLC), intracellular calcium, mitogen-activated protein kinase (MAPK), I-kappaB kinase/NF-kappaB and Rho. Can also be transactivated by cleaved F2r/Par1. Involved in modulation of inflammatory responses and regulation of innate and adaptive immunity, and acts as a sensor for proteolytic enzymes generated during infection. Generally is promoting inflammation. 1. Borensztajn, K. et al. (2008) The American journal of pathology 172, 309-20. PMID: 18202198 |
| 备注 | For research use only |
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