Anti-Human DKK4 Polyclonal Antibody|抗人DKK4多克隆抗体(靶标：人Dickkopf相关蛋白4)

Dickkopf-related protein 4 (DKK4) is a ~24 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.