| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Human |
| 靶标 | 39S ribosomal protein L12, mitochondrial; L12mt; MRP-L12; 5c5-2; Mitochondrial large ribosomal subunit protein bL12m; MRPL12; MRPL7; RPML12 |
| 免疫原 | E. coli - derived recombinant Human MRPL12 (His129-Glu198). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P52815 |
| 背景信息 | Large ribosomal subunit protein bL12m (MRPL12) is a ~21 kDa protein. As a component of the mitochondrial large ribosomal subunit, plays a role in mitochondrial translation. When present in mitochondria as a free protein not associated with the ribosome, associates with mitochondrial RNA polymerase POLRMT to activate transcription. Required for POLRMT stability. 1. Serre, V. et al. (2013) Biochimica et biophysica acta 1832, 1304-12. PMID: 23603806 2. Surovtseva, YV. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 17921-6. PMID: 22003127 3. Nouws, J. et al. (2016) The Journal of biological chemistry 291, 989-97. PMID: 26586915 |
| 备注 | For research use only |