Anti-Human CP Polyclonal Antibody|抗人CP多克隆抗体(靶标：人铜蓝蛋白)
- 货号：RB9THF643014
- 价格：面议
- 点击：404
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | Ceruloplasmin; 1.16.3.1; Ferroxidase; CP |
| 免疫原 | E. coli - derived recombinant Human CP (Asp789-Gly1065). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P00450 |
| 背景信息 | Ceruloplasmin (CP) is a ~122 kDa protein. Multifunctional blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane. Copper ions provide a large number of enzymatic activites. Oxidizes highly toxic ferrous ions to the ferric state for further incorporation onto apo-transferrins, catalyzes Cu(+) oxidation and promotes the oxidation of biogenic amines such as norepinephrin and serotonin. 1. Hochstrasser, H. et al. (2005) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19, 1851-3. PMID: 16150804 2. Stoj, C. et al. (2003) FEBS letters 554, 422-6. PMID: 14623105 3. Young, SN. et al. (1972) The Biochemical journal 129, 273-83. PMID: 4643313 4. Osaki, S. et al. (1966) The Journal of biological chemistry 241, 2746-51. PMID: 5912351 5. Park, YS. et al. (1999) FEBS letters 458, 133-6. PMID: 10481051 6. Shiva, S. et al. (2006) Nature chemical biology 2, 486-93. PMID: 16906150 |
| 备注 | For research use only |
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