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Anti-Human FOLR1 Recombinant Nanobody |抗人FOLR1纳米抗体(靶标:人叶酸受体1)

  • 货号:RB9THB825023
  • 价格:面议
  • 点击:473

产品介绍

产品参数

形态Liquid
宿主种属Alpaca
克隆性Monoclonal
抗体亚型VHH-8His-Cys-tag
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
内毒素水平Please contact with the lab for this information.
应用ELISA, FCM
种属反应性Homo sapiens (Human)
靶标ANPEP, AP-M, AP-N, APN, Alanyl aminopeptidase, Aminopeptidase M, Aminopeptidase N, CD13, EC:3.4.11.2, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, PEPN, gp150, hAPN
储存缓冲液0.01M PBS pH 7.4
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重构方法Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
登录号P15144
背景信息

Aminopeptidase N (FOLR1) is a ~109 kDa protein. Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization. May have a role in amino acid transport by acting as binding partner of amino acid transporter SLC6A19 and regulating its activity. FOLR1 is the therapeutic target of mirvetuximab soravtansine (Elahere).

备注For research use only
【仅供科学研究使用】

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