当前位置:首页>产品中心>单抗/多抗>Anti-E. coli groES Polyclonal Antibody|抗大肠杆菌groES多克隆抗体(靶标:大肠杆菌热休克蛋白GroES)

Anti-E. coli groES Polyclonal Antibody|抗大肠杆菌groES多克隆抗体(靶标:大肠杆菌热休克蛋白GroES)

  • 货号:RB9TJN912014
  • 价格:面议
  • 点击:763
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Escherichia coli (strain K12)
靶标10 kDa chaperonin, Chaperonin-10, Co-chaperonin GroES, Cpn10, groES, groS, mopB
免疫原E. coli - derived recombinant E. coli groES (Met1-Ala97).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
稳定性和储存Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
重构方法Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输条件In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P0A6F9
背景信息

Co-chaperonin GroES is a ~10 kDa protein. Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding, probably by preventing aggregation and by entropically destabilizing folding intermediates. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. Regulates the ATPase activity of GroEL.

1. Goloubinoff, P. et al. (1989) Nature 342, 884-9. PMID: 10532860
2. Tang, YC. et al. (2006) Cell 125, 903-14. PMID: 16751100
3. Martin, J. et al. (1991) Nature 352, 36-42. PMID: 1676490
4. Tang, YC. et al. (2008) The EMBO journal 27, 1458-68. PMID: 18418386
5. Apetri, AC. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 17351-5. PMID: 18987317
6. Chakraborty, K. et al. (2010) Cell 142, 112-22. PMID: 20603018
7. Gupta, AJ. et al. (2014) Journal of molecular biology 426, 2739-54. PMID: 24816391
8. Kusukawa, N. et al. (1989) The EMBO journal 8, 3517-21. PMID: 2573517
9. Hemmingsen, SM. et al. (1988) Nature 333, 330-4. PMID: 2897629
备注For research use only
【仅供科学研究使用】

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