| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse, Rat, Human |
| 靶标 | CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin |
| 免疫原 | E. coli - derived recombinant Human NOCT (Thr120-Ser431). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9UK39 |
| 背景信息 | Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis. 1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539 2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 通用型抗体标记物保存液 | 6371 |
| HRP标记抗体保存液 | 6621 |
| Biotin标记抗体保存液 | 6861 |
| FITC标记抗体保存液 | 6526 |
| Myc鼠单抗标签 | 6595 |
| HRP-Myc鼠单抗标签 | 6637 |
| Flag鼠单抗标签 | 7032 |
| HRP-Flag鼠单抗标签 | 6740 |
| GFP鼠单抗标签 | 6715 |
| HRP-GFP鼠单抗标签 | 6518 |
| GST鼠单抗标签 | 6616 |
| HRP-GST鼠单抗标签 | 6580 |
| HA鼠单抗标签 | 6938 |
| HRP-HA鼠单抗标签 | 6781 |
| His鼠单抗标签 | 6617 |
| HRP-His鼠单抗标签 | 6598 |
| MBP鼠单抗标签 | 6486 |
| HRP-MBP鼠单抗标签 | 6848 |
| mCherry鼠单抗标签 | 6399 |
| RFP-鼠单抗标签 | 6635 |