当前位置:首页>产品中心>单抗/多抗>Anti-Human NOCT Polyclonal Antibody|抗人NOCT多克隆抗体(靶标:人夜蛋白/Nocturnin)

Anti-Human NOCT Polyclonal Antibody|抗人NOCT多克隆抗体(靶标:人夜蛋白/Nocturnin)

  • 货号:RB9THA929014
  • 价格:面议
  • 点击:179

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Rat, Human
靶标CCR4, CCRN4L, Carbon catabolite repression 4-like protein, EC:3.1.3.108, NOC, NOCT, Nocturnin
免疫原E. coli - derived recombinant Human NOCT (Thr120-Ser431).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9UK39
背景信息

Nocturnin is a ~48 kDa protein. Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Represses translation and promotes degradation of target mRNA molecules. Plays an important role in post-transcriptional regulation of metabolic genes under circadian control. Exerts a rhythmic post-transcriptional control of genes necessary for metabolic functions including nutrient absorption, glucose/insulin sensitivity, lipid metabolism, adipogenesis, inflammation and osteogenesis.

1. Estrella, MA. et al. (2019) Nature communications 10, 2367. PMID: 31147539
2. Abshire, ET. et al. (2018) Nucleic acids research 46, 6257-6270. PMID: 29860338
备注For research use only
【仅供科学研究使用】

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