Anti-Human ATF6 Polyclonal Antibody|抗人ATF6多克隆抗体(靶标：人激活转录因子6)

形态	Liquid
宿主种属	Rabbit
克隆性	Polyclonal
抗体亚型	IgG
纯化方式	Purified by antigen affinity column.
内毒素水平	Please contact with the lab for this information.
应用	ELISA, IHC, WB
种属反应性	Rat, Human, Mouse
靶标	ATF6, ATF6-alpha, Activating transcription factor 6 alpha, Cyclic AMP-dependent transcription factor ATF-6 alpha, Processed cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transc
免疫原	E. coli - derived recombinant Human ATF6 (Ala547-Gln670).
储存缓冲液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明	ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号	P18850
背景信息	Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6) is a ~74 kDa protein. Precursor of the transcription factor form (Processed cyclic AMP-dependent transcription factor ATF-6 alpha), which is embedded in the endoplasmic reticulum membrane. Endoplasmic reticulum stress promotes processing of this form, releasing the transcription factor form that translocates into the nucleus, where it activates transcription of genes involved in the unfolded protein response (UPR). 1. Haze, K. et al. (1999) Molecular biology of the cell 10, 3787-99. PMID: 10564271 2. Yoshida, H. et al. (2001) Molecular and cellular biology 21, 1239-48. PMID: 11158310 3. Yoshida, H. et al. (2001) Cell 107, 881-91. PMID: 11779464
备注	For research use only

【仅供科学研究使用】

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