当前位置:首页>产品中心>单抗/多抗>Anti-Human ATP6V1C1 Polyclonal Antibody|抗人ATP6V1C1多克隆抗体(靶标:人V型质子ATP酶C1亚基)

Anti-Human ATP6V1C1 Polyclonal Antibody|抗人ATP6V1C1多克隆抗体(靶标:人V型质子ATP酶C1亚基)

  • 货号:RB9THB838024
  • 价格:面议
  • 点击:877
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Rat, Mouse, Human
靶标ATP6C, ATP6D, ATP6V1C1, V-ATPase subunit C 1, V-type proton ATPase subunit C 1, VATC, Vacuolar proton pump subunit C 1
免疫原E. coli - derived recombinant Human ATP6V1C1 (Met1-Lys382).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P21283
背景信息

V-type proton ATPase subunit C 1 (ATP6V1C1) is a ~43 kDa protein. Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.

1. Wang, L. et al. (2020) Molecular cell 80, 501-511.e3. PMID: 33065002
备注For research use only
【仅供科学研究使用】

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