Anti-Human SEPTIN2 Polyclonal Antibody|抗人SEPTIN2多克隆抗体(靶标：人分隔蛋白2/Septin-2)
- 货号：RB9THC185014
- 价格：面议
- 点击：220
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | DIFF6, KIAA0158, NEDD-5, NEDD5, Neural precursor cell expressed developmentally down-regulated protein 5, SEPT2, SEPTIN2, Septin-2 |
| 免疫原 | E. coli - derived recombinant Human SEPTIN2 (Gly19-Val361). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q15019 |
| 背景信息 | Septin-2 (SEPTIN2) is a ~41 kDa protein. Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. 1. Kuo, YC. et al. (2015) Journal of cell science 128, 923-34. PMID: 25588830 |
| 备注 | For research use only |
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