当前位置:首页>产品中心>单抗/多抗>Anti-Human PARD3 Polyclonal Antibody|抗人PARD3多克隆抗体(靶标:人Par-3家族细胞极性调节因子)

Anti-Human PARD3 Polyclonal Antibody|抗人PARD3多克隆抗体(靶标:人Par-3家族细胞极性调节因子)

  • 货号:RB9THC188024
  • 价格:面议
  • 点击:188

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Rat, Mouse
靶标ASIP, Atypical PKC isotype-specific-interacting protein, CTCL tumor antigen se2-5, PAR-3, PAR3, PAR3-alpha, PAR3A, PARD-3, PARD3, Partitioning defective 3 homolog
免疫原E. coli - derived recombinant Human PARD3 (Arg584-Lys686).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q8TEW0
背景信息

Partitioning defective 3 homolog (PARD3) is a ~151 kDa protein. Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination. Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly.

1. Johansson, A. et al. (2000) Journal of cell science 113 ( Pt 18), 3267-75. PMID: 10954424
2. Chen, X. et al. (2017) Human mutation 38, 378-389. PMID: 27925688
3. Joberty, G. et al. (2000) Nature cell biology 2, 531-9. PMID: 10934474
4. Khazaei, MR. et al. (2009) The Journal of biological chemistry 284, 33571-9. PMID: 19812038
备注For research use only
【仅供科学研究使用】

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