Anti-Human PMPCB Polyclonal Antibody|抗人PMPCB多克隆抗体(靶标：人线粒体加工肽酶β亚基)
- 货号：RB9THC189014
- 价格：面议
- 点击：972
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat, Mouse |
| 靶标 | Beta-MPP, EC:3.4.24.64, MPPB, Mitochondrial-processing peptidase subunit beta, P-52, PMPCB |
| 免疫原 | E. coli - derived recombinant Human PMPCB (Arg59-Asp489). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O75439 |
| 背景信息 | Mitochondrial-processing peptidase subunit beta (PMPCB) is a ~54 kDa protein. Catalytic subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins (Probable). Preferentially, cleaves after an arginine at position P2. Required for PINK1 turnover by coupling PINK1 mitochondrial import and cleavage, which results in subsequent PINK1 proteolysis. 1. Vögtle, FN. et al. (2018) American journal of human genetics 102, 557-573. PMID: 29576218 2. Greene, AW. et al. (2012) EMBO reports 13, 378-85. PMID: 22354088 |
| 备注 | For research use only |
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