| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | 130 kDa leucine-rich protein, GP130, LRP 130, LRP130, LRPPRC, Leucine-rich PPR motif-containing protein, mitochondrial |
| 免疫原 | E. coli - derived recombinant Human LRPPRC (Thr385-Asp725). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P42704 |
| 背景信息 | Leucine-rich PPR motif-containing protein, mitochondrial (LRPPRC) is a ~157 kDa protein. May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. Positively modulates nuclear export of mRNAs containing the EIF4E sensitivity element (4ESE) by binding simultaneously to both EIF4E and the 4ESE and acting as a platform for assembly for the RNA export complex. Also binds to exportin XPO1/CRM1 to engage the nuclear pore and traffic the bound mRNAs to the cytoplasm. May bind mature mRNA in the nucleus outer membrane. 1. Topisirovic, I. et al. (2009) The EMBO journal 28, 1087-98. PMID: 19262567 2. Volpon, L. et al. (2017) RNA (New York, N.Y.) 23, 927-937. PMID: 28325843 3. Zou, J. et al. (2013) The Biochemical journal 454, 447-57. PMID: 23822101 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5519 |
| 金刚烷胺单抗 | 5575 |
| 卡那霉素单抗 | 5726 |
| 黄曲霉毒素M1(AFM1)单抗 | 5691 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5877 |
| 帕托珠利(妥曲珠利砜)单抗 | 5595 |
| 泰乐菌素单抗 | 5645 |
| 替米考星单抗 | 5761 |
| 新霉素单抗 | 5748 |
| 安普霉素单抗 | 5687 |
| 三聚氰胺(MEL)单抗 | 5598 |
| 双氟沙星单抗 | 5549 |
| 西地那非单抗 | 5665 |
| 阿苯达唑单抗 | 5455 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5625 |
| 氟苯尼考单抗 | 5658 |
| 诺龙单抗 | 5730 |
| 达氟沙星单抗 | 5849 |
| 培氟沙星单抗 | 5711 |
| 庆大霉素单抗 | 5860 |