| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72 |
| 免疫原 | E. coli - derived recombinant Human DDX17 (Glu137-Gly556). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q92841 |
| 背景信息 | Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. 1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182 2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867 3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728 4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
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| CRP单克隆抗体 | 7588 |
| 猫胰脂肪酶单克隆抗体 | 7163 |
| 马SAA单克隆抗体 | 7517 |
| 犬腺病毒单克隆抗体 | 6902 |
| 犬轮状病毒单克隆抗体 | 6976 |
| 犬血红蛋白单克隆抗体 | 7916 |
| 犬胰脂肪酶单克隆抗体 | 6789 |
| 犬松弛素单克隆抗体 | 7154 |
| 犬冠状病毒单克隆抗体 | 7167 |
| 犬瘟病毒单克隆抗体 | 6871 |
| 犬细小病毒单克隆抗体 | 7328 |
| 猫瘟病毒单克隆抗体 | 7428 |
| 猫疱疹病毒单克隆抗体 | 7199 |
| 猫杯状病毒单克隆抗体 | 7615 |
| 猫SAA单克隆抗体 | 7268 |
| 犬CRP单克隆抗体 | 7800 |
| 犬、猫IgG单克隆抗体 | 7143 |