Anti-Human DDX17 Polyclonal Antibody|抗人DDX17多克隆抗体(靶标：人DEAD盒多肽17)
- 货号：RB9THC205014
- 价格：面议
- 点击：211
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse |
| 靶标 | DDX17, DEAD box protein 17, DEAD box protein p72, DEAD box protein p82, EC:3.6.4.13, Probable ATP-dependent RNA helicase DDX17, RNA-dependent helicase p72 |
| 免疫原 | E. coli - derived recombinant Human DDX17 (Glu137-Gly556). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q92841 |
| 背景信息 | Probable ATP-dependent RNA helicase DDX17 is a ~80 kDa protein. As an RNA helicase, unwinds RNA and alters RNA structures through ATP binding and hydrolysis. Involved in multiple cellular processes, including pre-mRNA splicing, alternative splicing, ribosomal RNA processing and miRNA processing, as well as transcription regulation. Regulates the alternative splicing of exons exhibiting specific features. For instance, promotes the inclusion of AC-rich alternative exons in CD44 transcripts. This function requires the RNA helicase activity. 1. Hönig, A. et al. (2002) Molecular and cellular biology 22, 5698-707. PMID: 12138182 2. Germann, S. et al. (2012) Oncogene 31, 4536-49. PMID: 22266867 3. Dardenne, E. et al. (2012) Nature structural & molecular biology 19, 1139-46. PMID: 23022728 4. Dardenne, E. et al. (2014) Cell reports 7, 1900-13. PMID: 24910439 |
| 备注 | For research use only |
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