| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | ACADVL, EC:1.3.8.9, VLCAD, Very long-chain specific acyl-CoA dehydrogenase, mitochondrial |
| 免疫原 | E. coli - derived recombinant Human ACADVL (Glu96-Phe655). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | P49748 |
| 背景信息 | Very long-chain acyl-CoA dehydrogenase, mitochondrial (ACADVL) is a ~70 kDa protein. Very long-chain specific acyl-CoA dehydrogenase is one of the acyl-CoA dehydrogenases that catalyze the first step of mitochondrial fatty acid beta-oxidation (FAO), breaking down fatty acids into acetyl-CoA and allowing the production of energy from fats. The first step of FAO consists in the proR-proR stereospecific alpha, beta-dehydrogenation of fatty acyl-CoA thioesters using the electron transfer flavoprotein (ETF) as their physiologic electron acceptor, resulting in the formation of trans-2-enoyl-CoA ((2E)-enoyl-CoA). Among the different mitochondrial acyl-CoA dehydrogenases, very long-chain specific acyl-CoA dehydrogenase acts specifically on fatty acyl-CoAs with saturated 12 to 24 carbons long primary chains. 1. He, M. et al. (2007) American journal of human genetics 81, 87-103. PMID: 17564966 2. McAndrew, RP. et al. (2008) The Journal of biological chemistry 283, 9435-43. PMID: 18227065 3. Aoyama, T. et al. (1995) American journal of human genetics 57, 273-83. PMID: 7668252 4. Souri, M. et al. (1998) The Journal of biological chemistry 273, 4227-31. PMID: 9461620 5. Souri, M. et al. (1998) FEBS letters 426, 187-90. PMID: 9599005 6. Souri, M. et al. (1998) European journal of biochemistry 257, 592-8. PMID: 9839948 7. He, M. et al. (2011) Molecular genetics and metabolism 102, 418-29. PMID: 21237683 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 空肠弯曲菌单克隆抗体 | 7491 |
| 人触珠蛋白单克隆抗体 | 7677 |
| 贾第鞭毛虫单克隆抗体 | 7343 |
| 阿米巴单克隆抗体 | 7851 |
| 胃蛋白酶单克隆抗体 | 7372 |
| 胃蛋白酶原II单克隆抗体 | 7557 |
| 胃蛋白酶原I单克隆抗体 | 7288 |
| 艰难梭菌毒素A单克隆抗体 | 7438 |
| 艰难梭菌毒素B单克隆抗体 | 7733 |
| 艰难梭菌GDH单克隆抗体 | 7741 |
| 诺如病毒单克隆抗体 | 7232 |
| 伤寒沙门氏菌单克隆抗体 | 7308 |
| 鼠疫耶尔森菌F1单克隆抗体 | 6831 |
| 幽门螺杆菌单克隆抗体 | 7346 |
| 钙卫蛋白单克隆抗体 | 7134 |
| 乳铁蛋白单克隆抗体 | 7468 |
| 转铁蛋白单克隆抗体 | 7465 |
| 血红蛋白单克隆抗体 | 7201 |
| 腺病毒单克隆抗体 | 7415 |
| 轮状病毒单克隆抗体 | 7788 |