Anti-Human LUZP1 Polyclonal Antibody|抗人LUZP1多克隆抗体(靶标：人亮氨酸拉链蛋白1)
- 货号：RB9THC252014
- 价格：面议
- 点击：381
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Rat |
| 靶标 | Filamin mechanobinding actin cross-linking protein, Fimbacin, LUZP1, Leucine zipper protein 1 |
| 免疫原 | E. coli - derived recombinant Human LUZP1 (Met157-Gln350). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q86V48 |
| 背景信息 | Leucine zipper protein 1 (LUZP1) is a ~120 kDa protein. F-actin cross-linking protein. Stabilizes actin and acts as a negative regulator of primary cilium formation. Positively regulates the phosphorylation of both myosin II and protein phosphatase 1 regulatory subunit PPP1R12A/MYPT1 and promotes the assembly of myosin II stacks within actin stress fibers. Inhibits the phosphorylation of myosin light chain MYL9 by DAPK3 and suppresses the constriction velocity of the contractile ring during cytokinesis. Binds to microtubules and promotes epithelial cell apical constriction by up-regulating levels of diphosphorylated myosin light chain (MLC) through microtubule-dependent inhibition of MLC dephosphorylation by myosin phosphatase. 1. Wang, J. et al. (2019) Biochemistry 58, 4737-4743. PMID: 30990684 2. Gonçalves, J. et al. (2020) The Journal of cell biology 219. PMID: 32496561 3. Wang, L. et al. (2024) Cellular and molecular life sciences : CMLS 81, 248. PMID: 38832964 4. Hyodo, T. et al. (2024) The FEBS journal 291, 927-944. PMID: 38009294 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 7013 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6520 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6942 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6847 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6592 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6452 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6726 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6440 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6318 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6450 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6394 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（6种） | 6576 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6314 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6562 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（8种） | 6642 |
| 单抗融合无忧套装 | 6706 |
| 即用型单抗细胞融合/亚克培养基 | 6419 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6745 |
| 通用型抗体稀释液 | 6320 |
| HRP酶标抗体稀释液 | 6537 |