| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | EC:2.1.1.-, NOL1/NOP2/Sun and PUA domain-containing protein 1, NOL1/NOP2/Sun domain family member 6, NOPD1, NSUN6, tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 |
| 免疫原 | E. coli - derived recombinant Human NSUN6 (Met1-Thr469). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q8TEA1 |
| 背景信息 | tRNA (cytosine(72)-C(5))-methyltransferase NSUN6 is a ~51 kDa protein. S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in tRNA(Thr)(TGT) and tRNA(Cys)(GCA). In vitro also methylates tRNA(Thr)(AGT). Methylation requires, in the acceptor stem region, the presence of the 3'-CCA terminus, the target site C72, the discriminator base U73, and the second and third base pairs (2:71 and 3:70) in the tRNA substrates. 1. Haag, S. et al. (2015) RNA (New York, N.Y.) 21, 1532-43. PMID: 26160102 2. Long, T. et al. (2016) The Journal of biological chemistry 291, 24293-24303. PMID: 27703015 3. Liu, RJ. et al. (2017) Nucleic acids research 45, 6684-6697. PMID: 28531330 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 羊抗鸡IgY抗体(精品) | 7484 |
| 鼠抗人IgG(单抗) | 7011 |
| 鼠抗人IgM(单抗) | 7280 |
| 新冠病毒N单抗IgG人源化质控品 | 7771 |
| 新冠病毒N单抗IgM人源化质控品 | 7417 |
| 三聚氰胺单抗 | 7018 |
| 纳他霉素单抗 | 7411 |
| 孔雀石绿单抗 | 7093 |
| 隐性孔雀石绿单抗 | 7213 |
| 微囊藻毒素LR单抗 | 7116 |
| 黄曲霉毒素B1单抗 | 6840 |
| 黄曲霉毒素M1单抗 | 6423 |
| T2毒素单抗 | 6860 |
| 赭曲霉毒素单抗 | 6686 |
| 呕吐毒素单抗 | 6767 |
| 伏马毒素单抗 | 7077 |
| 黄曲霉总量单抗B1 | 6261 |
| 黄曲霉总量单抗B2 | 6778 |
| 黄曲霉总量单抗G1 | 6543 |
| 黄曲霉总量单抗G2 | 6419 |