Anti-Mouse CD150/SLAMF1 Polyclonal Antibody|抗小鼠CD150/SLAMF1多克隆抗体(靶标：小鼠SLAM家族成员1/CD150)
- 货号：RB9TMC275014
- 价格：面议
- 点击：579
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | CD150, CDw150, IPO-3, SLAM, SLAM family member 1, SLAMF1, Signaling lymphocytic activation molecule |
| 免疫原 | E. coli - derived recombinant Mouse CD150/SLAMF1 (Asp31-Cys232). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q9QUM4 |
| 背景信息 | Signaling lymphocytic activation molecule (CD150/SLAMF1) is a ~38 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. SLAMF1-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAMF1 signaling seem to exist: one depending on SH2D1A (and perhaps SH2D1B) and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates. 1. Howie, D. et al. (2002) Blood 100, 2899-907. PMID: 12351401 2. Aversa, G. et al. (1997) Journal of immunology (Baltimore, Md. : 1950) 158, 4036-44. PMID: 9126961 3. Latour, S. et al. (2001) Nature immunology 2, 681-90. PMID: 11477403 4. Cannons, JL. et al. (2004) Immunity 21, 693-706. PMID: 15539155 5. Chen, R. et al. (2006) Molecular and cellular biology 26, 5559-68. PMID: 16847311 6. Wang, N. et al. (2004) The Journal of experimental medicine 199, 1255-64. PMID: 15123745 7. Yusuf, I. et al. (2010) Journal of immunology (Baltimore, Md. : 1950) 185, 190-202. PMID: 20525889 8. Wang, N. et al. (2006) American journal of respiratory cell and molecular biology 35, 206-10. PMID: 16528012 9. Griewank, K. et al. (2007) Immunity 27, 751-62. PMID: 18031695 |
| 备注 | For research use only |
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