| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycerophosphocholine esterase, EC:3.1.1.47, Group-VIIA phospholipase A2, LDL-PLA(2), LDL-associated phospholipase A2, PAF 2-acylhydrola |
| 免疫原 | E. coli - derived recombinant Mouse LpPLA2/PLA2G7/PAF-AH (Phe22-Asn440). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q60963 |
| 背景信息 | Platelet-activating factor acetylhydrolase (LpPLA2/PLA2G7) is a ~49 kDa protein. Lipoprotein-associated calcium-independent phospholipase A2 involved in phospholipid catabolism during inflammatory and oxidative stress response. At the lipid-aqueous interface, hydrolyzes the ester bond of fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity). Specifically targets phospholipids with a short-chain fatty acyl group at sn-2 position. Can hydrolyze phospholipids with long fatty acyl chains, only if they carry oxidized functional groups. Hydrolyzes and inactivates platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine), a potent pro-inflammatory signaling lipid that acts through PTAFR on various innate immune cells. 1. Stafforini, DM. et al. (1999) The Journal of biological chemistry 274, 7018-24. PMID: 10066756 2. Gardner, AA. et al. (2008) The Journal of biological chemistry 283, 17099-106. PMID: 18434304 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 阿苯达唑砜单抗 | 5510 |
| 金刚烷胺单抗 | 5560 |
| 卡那霉素单抗 | 5716 |
| 黄曲霉毒素M1(AFM1)单抗 | 5686 |
| 群勃龙(孕三烯酮)(去甲雄三烯醇酮)单抗 | 5861 |
| 帕托珠利(妥曲珠利砜)单抗 | 5592 |
| 泰乐菌素单抗 | 5639 |
| 替米考星单抗 | 5742 |
| 新霉素单抗 | 5739 |
| 安普霉素单抗 | 5674 |
| 三聚氰胺(MEL)单抗 | 5589 |
| 双氟沙星单抗 | 5537 |
| 西地那非单抗 | 5656 |
| 阿苯达唑单抗 | 5450 |
| 醋酸甲羟孕酮(醋酸甲孕酮)单抗 | 5614 |
| 氟苯尼考单抗 | 5646 |
| 诺龙单抗 | 5721 |
| 达氟沙星单抗 | 5840 |
| 培氟沙星单抗 | 5701 |
| 庆大霉素单抗 | 5849 |