当前位置：首页>产品中心>单抗/多抗>Anti-Mouse CDw210b/IL10RB Polyclonal Antibody|抗小鼠CDw210b/IL10RB多克隆抗体(靶标：小鼠白细胞介素10受体β亚基/CDw210b)
Anti-Mouse CDw210b/IL10RB Polyclonal Antibody|抗小鼠CDw210b/IL10RB多克隆抗体(靶标：小鼠白细胞介素10受体β亚基/CDw210b)
- 货号：RB9TMC339014
- 价格：面议
- 点击：1173
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Mouse |
| 靶标 | CDw210b, CRF2-4, CRFB4, Cytokine receptor class-II member 4, Cytokine receptor family 2 member 4, D21S58, D21S66, IL-10 receptor subunit beta, IL-10R subunit 2, IL-10R subunit beta, IL-10R2, IL-10RB, |
| 免疫原 | E. coli - derived recombinant Mouse CDw210b/IL10RB (Met20-Asn214). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q61190 |
| 背景信息 | Interleukin-10 receptor subunit beta (CDw210b/IL10RB) is a ~39 kDa protein. Shared cell surface receptor required for the activation of five class 2 cytokines: IL10, IL22, IL26, IL28, and IFNL1. The IFNLR1/IL10RB dimer is a receptor for the cytokine ligands IFNL2 and IFNL3 and mediates their antiviral activity. The ligand/receptor complex stimulate the activation of the JAK/STAT signaling pathway leading to the expression of IFN-stimulated genes (ISG), which contribute to the antiviral state. |
| 备注 | For research use only |
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