Anti-Human RAPGEF1 Polyclonal Antibody|抗人RAPGEF1多克隆抗体(靶标：人Rap鸟苷酸交换因子1/C3G)
- 货号：RB9THC394014
- 价格：面议
- 点击：166
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CRK SH3-binding GNRP, GRF2, Guanine nucleotide-releasing factor 2, Protein C3G, RAPGEF1, Rap guanine nucleotide exchange factor 1 |
| 免疫原 | E. coli - derived recombinant Human RAPGEF1 (His842-Thr1077). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13905 |
| 背景信息 | Rap guanine nucleotide exchange factor 1 (RAPGEF1) is a ~120 kDa protein. Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. 1. Sakakibara, A. et al. (2002) Journal of cell science 115, 4915-24. PMID: 12432078 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 痢疾志贺氏菌单克隆抗体 | 7559 |
| 沙门氏菌单克隆抗体 | 7353 |
| 乙型副伤寒沙门氏菌单克隆抗体 | 7916 |
| A族链球菌单克隆抗体 | 7510 |
| 甲型副伤寒沙门氏菌单抗 | 7288 |
| 麻疹病毒单克隆抗体 | 7520 |
| HBeAg单克隆抗体 | 7498 |
| 新型冠状病毒（SARS-COV-2）NP蛋白单克隆抗体 | 6999 |
| 呼吸道腺病毒单克隆抗体 | 7711 |
| 大肠杆菌单克隆抗体 | 7600 |
| LP-PLA2单克隆抗体 | 7566 |
| NT-PROBNP单克隆抗体 | 7312 |
| 半乳糖凝集素3单克隆抗体 | 7289 |
| D二聚体单克隆抗体 | 7310 |
| 肌钙蛋白单克隆抗体 | 7600 |
| 肌红蛋白单克隆抗体 | 7478 |
| AAT单克隆抗体 | 7269 |
| 人SAA单克隆抗体 | 7245 |
| 黏病毒抗性蛋白A单克隆抗体 | 7470 |
| 降钙素原单克隆抗体 | 7182 |