Anti-Human RAPGEF1 Polyclonal Antibody|抗人RAPGEF1多克隆抗体(靶标：人Rap鸟苷酸交换因子1/C3G)
- 货号：RB9THC394014
- 价格：面议
- 点击：244
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | CRK SH3-binding GNRP, GRF2, Guanine nucleotide-releasing factor 2, Protein C3G, RAPGEF1, Rap guanine nucleotide exchange factor 1 |
| 免疫原 | E. coli - derived recombinant Human RAPGEF1 (His842-Thr1077). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13905 |
| 背景信息 | Rap guanine nucleotide exchange factor 1 (RAPGEF1) is a ~120 kDa protein. Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Involved in cell branching and adhesion mediated by BCAR1-CRK-RAPGEF1 signaling and activation of RAP1. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth. 1. Sakakibara, A. et al. (2002) Journal of cell science 115, 4915-24. PMID: 12432078 |
| 备注 | For research use only |
相关产品:
| 产品名称 | 点击数 |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 7037 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6541 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6951 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6864 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6611 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6471 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6737 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6459 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6326 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6465 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（6种） | 6419 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（6种） | 6592 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6333 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装（8种） | 6575 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒（8种） | 6650 |
| 单抗融合无忧套装 | 6731 |
| 即用型单抗细胞融合/亚克培养基 | 6434 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6759 |
| 通用型抗体稀释液 | 6330 |
| HRP酶标抗体稀释液 | 6550 |