Anti-Human DGKZ Polyclonal Antibody|抗人DGKZ多克隆抗体(靶标：人二酰甘油激酶ζ)
- 货号：RB9THC693024
- 价格：面议
- 点击：509
产品介绍
产品参数
| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | DAG kinase zeta, DAGK6, DGK-zeta, DGKZ, Diacylglycerol kinase zeta, Diglyceride kinase zeta, EC:2.7.1.107, EC:2.7.1.93 |
| 免疫原 | E. coli - derived recombinant Human DGKZ (Gly411-Lys624). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13574 |
| 背景信息 | Diacylglycerol kinase zeta (DGKZ) is a ~103 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Does not exhibit an acyl chain-dependent substrate specificity among diacylglycerol species. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro but less efficiently and with a preference for alkylacylglycerols containing an arachidonoyl group. 1. Epand, RM. et al. (2004) Biochemistry 43, 14778-83. PMID: 15544348 2. Epand, RM. et al. (2007) Biochemistry 46, 14225-31. PMID: 18004883 3. Lung, M. et al. (2009) The Journal of biological chemistry 284, 31062-73. PMID: 19744926 4. Shulga, YV. et al. (2011) FEBS letters 585, 4025-8. PMID: 22108654 5. Gellett, AM. et al. (2012) Biochemical and biophysical research communications 422, 758-63. PMID: 22627129 6. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 7. Ding, L. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 5519-24. PMID: 9159104 |
| 备注 | For research use only |
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