| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | DAG kinase zeta, DAGK6, DGK-zeta, DGKZ, Diacylglycerol kinase zeta, Diglyceride kinase zeta, EC:2.7.1.107, EC:2.7.1.93 |
| 免疫原 | E. coli - derived recombinant Human DGKZ (Gly411-Lys624). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | Q13574 |
| 背景信息 | Diacylglycerol kinase zeta (DGKZ) is a ~103 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Also plays an important role in the biosynthesis of complex lipids (Probable). Does not exhibit an acyl chain-dependent substrate specificity among diacylglycerol species. Can also phosphorylate 1-alkyl-2-acylglycerol in vitro but less efficiently and with a preference for alkylacylglycerols containing an arachidonoyl group. 1. Epand, RM. et al. (2004) Biochemistry 43, 14778-83. PMID: 15544348 2. Epand, RM. et al. (2007) Biochemistry 46, 14225-31. PMID: 18004883 3. Lung, M. et al. (2009) The Journal of biological chemistry 284, 31062-73. PMID: 19744926 4. Shulga, YV. et al. (2011) FEBS letters 585, 4025-8. PMID: 22108654 5. Gellett, AM. et al. (2012) Biochemical and biophysical research communications 422, 758-63. PMID: 22627129 6. Sato, M. et al. (2013) Pharmacology 92, 99-107. PMID: 23949095 7. Ding, L. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 5519-24. PMID: 9159104 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5703 |
| 西马特罗单抗 | 5677 |
| 孕酮单抗 | 5878 |
| 氯霉素(CAP)单抗 | 5805 |
| 红霉素单抗 | 5777 |
| 地克珠利单抗 | 5586 |
| 无色孔雀石绿(LMG)单抗 | 5808 |
| 雌二醇单抗 | 5435 |
| 孔雀石绿(MG)单抗 | 5972 |
| 双酚A单抗 | 5742 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5615 |
| 己烯雌酚单抗 | 5612 |
| 莱克多巴胺(RAC)单抗 | 5779 |
| 林可霉素单抗 | 5955 |
| 抗青霉素受体单抗 | 5612 |
| 大观霉素单抗 | 5671 |
| 克伦特罗(CL)单抗 | 5892 |
| 沙拉沙星单抗(2H4) | 5701 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5875 |
| 磺胺类SAS单抗 | 5812 |