| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human |
| 靶标 | EC:1.1.1.105, EC:1.1.1.209, EC:1.1.1.315, EC:1.1.1.53, Human epidermal retinol dehydrogenase, Microsomal NAD(+)-dependent retinol dehydrogenase 4, RDH16, RODH4, Retinol dehydrogenase 16, RoDH-4, SDR9C |
| 免疫原 | E. coli - derived recombinant Human RDH16 (Arg28-Lys288). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O75452 |
| 背景信息 | Retinol dehydrogenase 16 (RDH16) is a ~35 kDa protein. Oxidoreductase with a preference for NAD. Oxidizes all-trans-retinol, 9-cis-retinol, 11-cis-retinol and 13-cis-retinol to the corresponding aldehydes. Has higher activity towards CRBP-bound retinol than with free retinol. Also oxidizes 3-alpha-hydroxysteroids. Oxidizes androstanediol and androsterone to dihydrotestosterone and androstanedione. 1. Jurukovski, V. et al. (1999) Molecular genetics and metabolism 67, 62-73. PMID: 10329026 2. Lapshina, EA. et al. (2003) Biochemistry 42, 776-84. PMID: 12534290 3. Gough, WH. et al. (1998) The Journal of biological chemistry 273, 19778-85. PMID: 9677409 4. Fiandalo, MV. et al. (2018) Oncotarget 9, 11227-11242. PMID: 29541409 |
| 备注 | For research use only |
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