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Anti-Human GAN Polyclonal Antibody|抗人GAN多克隆抗体(靶标:人巨轴索神经病蛋白/Gigaxonin)

  • 货号:RB9THD009014
  • 价格:面议
  • 点击:488

产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Mouse, Human
靶标GAN, GAN1, Gigaxonin, KLHL16, Kelch-like protein 16
免疫原E. coli - derived recombinant Human GAN (Gly270-Pro597).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q9H2C0
背景信息

Gigaxonin (GAN) is a ~67 kDa protein. Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.

备注For research use only
【仅供科学研究使用】

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