当前位置:首页>产品中心>单抗/多抗>Anti-Human SEC24C Polyclonal Antibody|抗人SEC24C多克隆抗体(靶标:人SEC24同源物C/COPII外壳组分)

Anti-Human SEC24C Polyclonal Antibody|抗人SEC24C多克隆抗体(靶标:人SEC24同源物C/COPII外壳组分)

  • 货号:RB9THD071014
  • 价格:面议
  • 点击:654
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human
靶标KIAA0079, Protein transport protein Sec24C, SEC24-related protein C, SEC24C
免疫原E. coli - derived recombinant Human SEC24C (Asp324-Ser1094).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号P53992
背景信息

Protein transport protein Sec24C is a ~118 kDa protein. Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Plays a central role in cargo selection within the COPII complex and together with SEC24D may have a different specificity compared to SEC24A and SEC24B. May more specifically package GPI-anchored proteins through the cargo receptor TMED10. May also be specific for IxM motif-containing cargos like the SNAREs GOSR2 and STX5.

1. Tani, K. et al. (1999) FEBS letters 447, 247-50. PMID: 10214955
2. Mancias, JD. et al. (2007) Molecular cell 26, 403-14. PMID: 17499046
3. Mancias, JD. et al. (2008) The EMBO journal 27, 2918-28. PMID: 18843296
4. Bonnon, C. et al. (2010) Journal of cell science 123, 1705-15. PMID: 20427317
备注For research use only
【仅供科学研究使用】

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