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Anti-Human WAPL Polyclonal Antibody|抗人WAPL多克隆抗体(靶标:人WAPL黏连蛋白释放因子)

  • 货号:RB9THD137014
  • 价格:面议
  • 点击:433
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产品介绍

产品参数

形态Liquid
宿主种属Rabbit
克隆性Polyclonal
抗体亚型IgG
纯化方式Purified by antigen affinity column.
内毒素水平Please contact with the lab for this information.
应用ELISA, IHC, WB
种属反应性Human, Mouse
靶标FOE, Friend of EBNA2 protein, KIAA0261, WAPAL, WAPL, WAPL cohesin release factor, Wings apart-like protein homolog
免疫原E. coli - derived recombinant Human WAPL (His641-Asp838).
储存缓冲液0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
产品使用说明ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000
登录号Q7Z5K2
背景信息

Wings apart-like protein homolog (WAPL) is a ~132 kDa protein. Regulator of sister chromatid cohesion in mitosis which negatively regulates cohesin association with chromatin. Involved in both sister chromatid cohesion during interphase and sister-chromatid resolution during early stages of mitosis. Couples DNA replication to sister chromatid cohesion. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair.

1. Yeh, C. et al. (2015) Current biology : CB 25, 2290-9. PMID: 26299517
备注For research use only
【仅供科学研究使用】

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