| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | 5'-3' exoribonuclease DXO, DOM3L, DOM3Z, DXO, DeNADding enzyme DXO, Decapping and exoribonuclease protein, Dom-3 homolog Z, EC:3.1.13.-, EC:3.6.1.-, NAD-capped RNA hydrolase DXO, NG6 |
| 免疫原 | E. coli - derived recombinant Human DXO (Thr31-Lys396). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O77932 |
| 背景信息 | Decapping and exoribonuclease protein (DXO) is a ~44 kDa protein. Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay. Preferentially acts on NAD-capped transcripts in response to environmental stress. Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation. 1. Jiao, X. et al. (2017) Cell 168, 1015-1027.e10. PMID: 28283058 2. Grudzien-Nogalska, E. et al. (2019) Nature chemical biology 15, 575-582. PMID: 31101919 3. Picard-Jean, F. et al. (2018) PloS one 13, e0193804. PMID: 29601584 4. Doamekpor, SK. et al. (2020) Nucleic acids research 48, 6136-6148. PMID: 32374864 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 新冠病毒S蛋白中和抗体ELISA半定量检测试剂盒 | 7052 |
| 新冠病毒(Delta)S蛋白中和抗体ELISA检测试剂盒 | 6554 |
| 新冠病毒(奥密克戎)S蛋白中和抗体ELISA检测试剂盒 | 6964 |
| 人抗新冠病毒S蛋白IgG抗体ELISA检测试剂盒 | 6874 |
| 人抗新冠病毒S蛋白IgM亚型抗体ELISA检测试剂盒 | 6619 |
| 人抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6484 |
| 人抗新冠病毒奥密克戎RBD蛋白IgG亚型抗体ELISA检测试剂盒 | 6750 |
| 抗新冠病毒N蛋白-IgG抗体ELISA检测试剂盒 | 6473 |
| 碱性磷酸酶-抗体快速标记试剂盒 | 6328 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(6种) | 6476 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(6种) | 6428 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒(6种) | 6603 |
| 鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(8种) | 6346 |
| 即用型小鼠单抗Ig类/亚类/亚型鉴定用酶标二抗套装(8种) | 6582 |
| 鼠单抗Ig类/亚类鉴定用ELISA试剂盒(8种) | 6661 |
| 单抗融合无忧套装 | 6747 |
| 即用型单抗细胞融合/亚克培养基 | 6446 |
| Frdbio®第三代抗体生物素标记试剂盒 | 6767 |
| 通用型抗体稀释液 | 6343 |
| HRP酶标抗体稀释液 | 6558 |