| 形态 | Liquid |
|---|---|
| 宿主种属 | Rabbit |
| 克隆性 | Polyclonal |
| 抗体亚型 | IgG |
| 纯化方式 | Purified by antigen affinity column. |
| 内毒素水平 | Please contact with the lab for this information. |
| 应用 | ELISA, IHC, WB |
| 种属反应性 | Human, Mouse, Rat |
| 靶标 | 5'-3' exoribonuclease DXO, DOM3L, DOM3Z, DXO, DeNADding enzyme DXO, Decapping and exoribonuclease protein, Dom-3 homolog Z, EC:3.1.13.-, EC:3.6.1.-, NAD-capped RNA hydrolase DXO, NG6 |
| 免疫原 | E. coli - derived recombinant Human DXO (Thr31-Lys396). |
| 储存缓冲液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 产品使用说明 | ELISA:1:5000-1:20000;IHC:1:50-1:500;WB:1:500-1:2000 |
| 登录号 | O77932 |
| 背景信息 | Decapping and exoribonuclease protein (DXO) is a ~44 kDa protein. Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA. The NAD-cap is present at the 5'-end of some RNAs and snoRNAs. In contrast to the canonical 5'-end N7 methylguanosine (m7G) cap, the NAD cap promotes mRNA decay. Preferentially acts on NAD-capped transcripts in response to environmental stress. Also acts as a non-canonical decapping enzyme that removes the entire cap structure of m7G capped or incompletely capped RNAs and mediates their subsequent degradation. 1. Jiao, X. et al. (2017) Cell 168, 1015-1027.e10. PMID: 28283058 2. Grudzien-Nogalska, E. et al. (2019) Nature chemical biology 15, 575-582. PMID: 31101919 3. Picard-Jean, F. et al. (2018) PloS one 13, e0193804. PMID: 29601584 4. Doamekpor, SK. et al. (2020) Nucleic acids research 48, 6136-6148. PMID: 32374864 |
| 备注 | For research use only |
| 产品名称 | 点击数 |
|---|---|
| 氯丙嗪单抗 | 5693 |
| 西马特罗单抗 | 5660 |
| 孕酮单抗 | 5870 |
| 氯霉素(CAP)单抗 | 5797 |
| 红霉素单抗 | 5768 |
| 地克珠利单抗 | 5573 |
| 无色孔雀石绿(LMG)单抗 | 5794 |
| 雌二醇单抗 | 5425 |
| 孔雀石绿(MG)单抗 | 5964 |
| 双酚A单抗 | 5722 |
| 呋喃妥因代谢物(2-NPAHD)单抗 | 5607 |
| 己烯雌酚单抗 | 5597 |
| 莱克多巴胺(RAC)单抗 | 5767 |
| 林可霉素单抗 | 5925 |
| 抗青霉素受体单抗 | 5608 |
| 大观霉素单抗 | 5657 |
| 克伦特罗(CL)单抗 | 5874 |
| 沙拉沙星单抗(2H4) | 5691 |
| 磺胺对甲氧嘧啶(SMD)单抗 | 5864 |
| 磺胺类SAS单抗 | 5793 |